Antibiofilm Potential of Metal Based Nanoparticles: Synthesis and Mode of Action

  • R Kaur Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India
  • M Khurana Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India
  • R K Virk Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India
  • A Sharma Department of Biotechnology and Bioinformatics, DAV, College, Sec-10, Chandigarh, India
Keywords: Biofilm, metals, Nanoparticles, Formulation methods


Biofilm refers to a group of microbes colonizing together and often adhered to a surface. The adherence is attributed to secretion of polymeric substances comprising of extracellular DNA, proteins, and polysaccharides thereby limiting the access and inhibitory activity of existing antimicrobial agents. Biofilm are a major cause of acute infections and pose immense clinical threat especially in conditions employing the use of invasive devices thus being a major source of mortality and morbidity. Hence there is a dire need to develop alternative treatment against biofilm-related infections. Advances in nanotechnology has opened new horizons. Nanoparticles derived from various metal present promising candidates to ameliorate biofilms owing to their antioxidant potential.


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How to Cite
R Kaur, Khurana, M., R K Virk, & A Sharma. (2018). Antibiofilm Potential of Metal Based Nanoparticles: Synthesis and Mode of Action. Journal of Multidisciplinary Research in Healthcare, 4(2), 77-81.