Oligoasthenozoospermic and Normozoospermic Indian Males Yielded Similar Fertilization Capability by Intracytoplasmic Sperm Injection

Abstract

Background: The present study evaluated the fertilization outcomes by intra-cytoplasmic sperm injection (ICSI) technique with oligoastheno-zoospermic (OAZ) compared to normozoospermic (NZ) semen.

Purpose: To find the fertilizing capability of human sperm in oligo-asthenozoospermic and normozoospermic semen samples.

Methods: Fresh semen ejaculates belonging to NZ and OAZ groups (n=50 in each group) patients attending the infertility clinics were evalu-ated for semen volume, sperm motility, and sperm concentration. Ferti-lization rates with ICSI along with post-capacitation motility and con-centration were studied in both groups.

Results: The motility and concentration in fresh semen samples patients of the NZ group (32.44±1.50%, 71.96±6.45 M/ml, respectively) were significantly (P<0.05) higher compared to the OAZ group (26.76±1.38, 10.31±0.48 M/ml, respectively).However, the results of our study re-vealed similar fertilization rates in-vitro by ICSI in the NZ (98%) and OAZ (98%) groups.

Conclusion: The in-vitro processing by the ICSI technique is an effective approach to achieving good fertilization rates in sub-fertile males.

  • Page Number : 51-58

  • Published Date : 2023-04-12

  • Keywords
    Capacitati, Intra-cytoplasmic sperm injection, sperm concentration, Sperm motility, Normozoospermia, Igoasthenozo-ospermia

  • DOI Number
    10.15415/jmrh.2023.92005

  • Authors
    Ram Dayal

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