3d8d13581898e6394431f5a 20231121043515576 chitu:chitu chitkarauniversitypublications@chitkara.edu.in WEB-FORM Journal of Multidisciplinary Research in Healthcare JMRH 23938536 23938544 10.15415/jmrh https://jmrh.chitkara.edu.in/ 10 05 2015 10 05 2015 2 1 10.15415/jmrh.2015.21 https://jmrh.chitkara.edu.in/2015/vol-2-no-01/ The Potential Role of Nicotine in the Treatment of Learning and Memory Impairment after REM Sleep Deprivation BRAINetwork Centre for Neurocognitive Sciences, School of Health Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian Kelantan, Malaysia IDRIS LONG NORLINDA ABD RASHID BRAINetwork Centre for Neurocognitive Sciences, School of Health Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian Kelantan, Malaysia Sleep depri vation has become a contributing factor to the world’s health concerns such as cardiovascular disease, mental illness and inattentiveness in occupationand decision making. It can also disturb synaptic plasticity that can lead to learning and memory impairment. Therefore, boosting cholinergic activity using acetylcholine imitator that can be found in the tobacco plant, known as nicotine, is essential in reversing the negative influences of sleep loss in the brain. Thus, studies on the effects of nicotine treatment on molecular mechanisms and structural changes of hippocampal brain cells are vital in order to gain more understanding and to overcome the detrimental consequencesof learning and memory impairment related to sleep divest. 10 05 2015 10 05 2015 17 30 10.15415/jmrh.2015.21002 https://jmrh.chitkara.edu.in/2015/the-potential-role-of-nicotine-in-the-treatment-of-learning-and-memory-impairment-after-rem-sleep-deprivation/