Hybrid Approach for Automatic Drug Dispensing and Control

Published: April 10, 2017

Authors

Naveen Kumar, S.N.Panda, Preethi Pradhan

Keywords
Automatic Drug delivery, Infusion pump, Open Loop, Closed Loop, Depth of Anaesthesia, BIS

Abstract

Clinical scenario for critically ill patients involves large number of medical devices, such as, bed side monitors that provide vital information about the admitted patient. Critically ill patients need prompt and perfect decision, so that lifesaving drugs can be delivered at a proper time. Moreover suggestions/ recommendations of a super specialist doctor may also be required in hospitals. The main problem in hospitals is lack of specialist doctors, so, patients are not able to approach to them on time. Automatic drug delivery using microprocessor/ microcontroller has improved tremendously in recent years due to advancement in Information and Communication Technology (ICT). This paper is focused on various Drug Delivery System Interfaces used in emergency cases to reduce manual intervention. We are proposing a hybrid approach for drug dispensing, which can work as open or closed loop system. Another feature of this system is that it can be controlled from a remote location, so is to provide virtual presence of a doctor. The system will help the doctor monitor the patient as per the immediate requirement and deliver drug remotely to patient using smart phone.

References

[1] Simanski, O., Schubert, A., Kaehler, R., Janda, M., Bajorat, J., Hofmockel, R. and Lampe, B., 2007, June. Automatic drug delivery in anaesthesia: From the beginning until now. In Control & Automation, 2007. MED’07. Mediterranean Conference on (pp. 1-6). IEEE.
[2] Ziv, Stephen D. Small, Paul Root Wo, A. (2000). Patient safety and simulation based medical education. Med Teach, 22(5), pp.489–495. https://doi.org/10.1080/01421590050110777
[3] Arney, D., Pajic, M., Goldman, J.M., Lee, I., Mangharam, R. and Sokolsky, O., 2010, April. Toward patient safety in closed-loop medical device systems. In Proceedings of the 1st ACM/IEEE International Conference on Cyber-Physical Systems (pp. 139–148). ACM https://doi.org/10.1145/1795194.1795214
[4] Huang, J., Ying-Ying Lu, Nayak, A. and Roy, R. (1999). Depth of anaesthesia estimation and control [using auditory evoked potentials]. IEEE Transactions on Biomedical Engineering, 46(1), pp.71–81. https://doi.org/10.1109/10.736759
[5] Kameneva, Tatiana et al. ‘A Comparison of Open-Loop And Closed-Loop Stimulation Strategies To Control Excitation Of Retinal Ganglion Cells’. Biomedical Signal Processing and Control 14 (2014): 164–174. Web. https://doi.org/10.1016/j.bspc.2014.07.015
[6] Dumont, Guy A., and J. Mark Ansermino. ‘Closed-Loop Control of Anesthesia: A Primer for Anesthesiologists’. Anesthesia & Analgesia 117.5 (2013): 1130– 1138. Web. https://doi.org/10.1213/ANE.0b013e3182973687
[7] Hayakawa, T., Haddad, W.M., Bailey, J.M. and Hovakimyan, N. (2005) ‘Passivity-Based Neural Adaptive Output Feedback Control for Nonlinear Nonnegative Dynamical Systems’, IEEE Transaction on Neural Network, vol. 16, March, pp. 387–398. https://doi.org/10.1109/TNN.2004.841782
[8] Lin, H., Beck, C. and Bloom, M. (2004). On the Use of Multivariable Piecewise- Linear Models for Predicting Human Response to Anesthesia. IEEE Transactions on Biomedical Engineering, 51(11), pp.1876–1887. https://doi.org/10.1109/TBME.2004.831541
[9] AGARWAL, J., PURI, G. and MATHEW, P. (2009). Comparison of closed loop vs. manual administration of propofol using the Bispectral index in cardiac surgery. Acta Anaesthesiologica Scandinavica, 53(3), pp.390–397. https://doi.org/10.1111/j.1399-6576.2008.01884.x
[10] Struys, M., De Smet, T., Versichelen, L., Van de Velde, S., Van den Broecke, R. and Mortier, E. (2001). Comparison of Closed-loop Controlled Administration of Propofol Using Bispectral Index as the Controlled Variable versus “Standard Practice” Controlled Administration. Anesthesiology, 95(1), pp.6–17. https://doi.org/10.1097/00000542-200107000-00007
[11] Soltesz, K., Dumont, G., van Heusden, K., Hagglund, T. and Ansermino, J.M., 2012, December. Simulated mid-ranging control of propofol and remifentanil using EEG-measured hypnotic depth of anaesthesia. In Decision and Control (CDC), 2012 IEEE 51st Annual Conference on (pp. 356-361). IEEE.
[12] Meystre, S., 2005. The current state of telemonitoring: a comment on the literature. Telemedicine Journal & e-Health, 11(1), pp.63–69. https://doi.org/10.1089/tmj.2005.11.63
[13] Fernandes, B., Afonso, J.A. and Simões, R., 2011, June. Vital signs monitoring and management using mobile devices. In 6th Iberian Conference on Information Systems and Technologies (CISTI 2011) (pp. 1-6). IEEE.
[14] Van Halteren, A.T., Bults, R.G.A., Wac, K.E., Konstantas, D., Widya, I.A., Dokovski, N.T., Koprinkov, G.T., Jones, V.M. and Herzog, R., 2004. Mobile patient monitoring: The mobihealth system.
[15] Yuan, B. and Herbert, J., 2011, March. Web-based real-time remote monitoring for pervasive healthcare. In Pervasive Computing and Communications Workshops (PERCOM Workshops), 2011 IEEE International Conference on (pp. 625-629). IEEE. https://doi.org/10.1109/PERCOMW.2011.5766964

How to Cite

Naveen Kumar, S.N.Panda, Preethi Pradhan. Hybrid Approach for Automatic Drug Dispensing and Control. J. Multidiscip. Res. Healthcare. 2017, 03, 69-77
Hybrid Approach for Automatic Drug Dispensing and Control

Current Issue

PeriodicityBiannually
Issue-1October
Issue-2April
ISSN Print2393-8536
ISSN Online2393-8544
RNI No.CHAENG/2014/57978
OA Policy

Publisher's policy of the journal at Sherpa UK for the submitted, accepted, and published articles. Click OAPolicy

Plan-S Compliance

To check compliance, one has to use the Journal Check Tool (JCT). This tool provided by cOAlition S (European funders) for the researchers (fundee) to check the compliance with the journal.

Recommend journal to your library

You can recommend the journal being a researcher or faculty member to your library. We will post a copy of the Journal to your library on your behalf at free of cost.
Click here: Recommend Journal

Preprint Arxiv Submission

The authors are encouraged to submit the author’s copy (preprint) to appropriate preprint archives e.g. https://arxiv.org and/or on https://indiarxiv.org or institutional repositories (e.g., D Space) before paper acceptance by the editor of Journal. After publications of the paper author(s) should mention the citation information, title and abstract along with DOI number of the publication carefully on the required page of the depository(ies).

Contact:

Phone: +91-172-2741000, +91-172-4691800
Email : editor.jmrh@chitkara.edu.in

Abstract and Indexing

This work is licensed under a Creative Commons Attribution 4.0 International License.

Articles in Journal of Multidisciplinary Research in Healthcare by Chitkara University Publications are Open Access articles that are published with licensed under a Creative Commons Attribution- CC-BY 4.0 International License. Based on a work at https://jmrh.chitkara.edu.in/. This license permits one to use, remix, tweak and reproduction in any medium, even commercially provided one give credit for the original creation.

View Legal Code of the above-mentioned license, https://creativecommons.org/licenses/by/4.0/legalcode

View Licence Deed here https://creativecommons.org/licenses/by/4.0/

Creative Commons License

Journal of Multidisciplinary Research in Healthcare by Chitkara University Publications is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://jmrh.chitkara.edu.in/

Members